Abstract: Liangzhou donkey was an excellent local donkey kinds, the donkey meat, skin, milk products and so forth which had pharmacological efficacy such as invigorating vital energy, nourishing blood and aphrodisiac, and played an irreplaceable utilization value. However, for the past ten years, as the mechanization development in the country and consumer demand on the donkey product quality, the standing stock of Liangzhou donkey decreased soon compared to 1980s. In addition, due to Qingyang donkey genes introduction to local area, Liangzhou donkey characteristics has changed a lot such as its height and length significantly increased by 10 cm. Based on this, Liangzhou donkey was identified as Gansu provincial livestock and poultry genetic resources protected variety by Gansu agricuture and animal husbandry office in 2009. This article argued the development and utilization of Liangzhou donkey from four aspacts which are policy protection, breeding improvement, product development and consumption propaganda.