Effects of depilation by drugs on serum hormone and enzyme levels of Liaoning Cashmere goat

This study was to examine effects of depilation by drugs on blood hormone and enzyme levels of Liaoning Cashmere goat. Twelve fouryearold female Liaoning Cashmere goats were divided into four groups randomly, in which control group was without any treatment, groupⅠ was treated with subcutaneous implantation of melatonin (60 mggoat-1), groupⅡ was subcutaneous implantation of melatonin plus injected muscularly with cyclophosphamide (26 mgkg-1), and groupⅢ was only injected with cyclophosphamide (26 mgkg-1). To determine the levels of several serum hormones and enzymes, blood samples of goats were collected and tested at 0, 30 and 50 d after treatments. Results obtained from the study showed that subcutaneous implantation of melatonin increased the levels of alpha amylase (AAMY) and alkaline phosphatase (ALP), but reduced the levels of adrenocorticotrophic hormone (ACTH), cortisol (Cor), epidermal growth factor (EGF) and creatine phosphokinase (CPK). Injection of the cyclophosphamide increased the levels of creatine phosphokinase, alpha amylase and cortisol, and reduced the levels of alkaline phosphatase and melatonin (MT).